Detalhe da pesquisa
1.
Design, Synthesis, and In Vivo Evaluation of C1-Linked 4,5-Epoxymorphinan Haptens for Heroin Vaccines.
Molecules
; 27(5)2022 Feb 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35268659
2.
Bivalent Conjugate Vaccine Induces Dual Immunogenic Response That Attenuates Heroin and Fentanyl Effects in Mice.
Bioconjug Chem
; 32(11): 2295-2306, 2021 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34076427
3.
Novel Vaccine That Blunts Fentanyl Effects and Sequesters Ultrapotent Fentanyl Analogues.
Mol Pharm
; 17(9): 3447-3460, 2020 09 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32787282
4.
Synthesis of a deuterated 6-AmHap internal standard for the determination of hapten density in a heroin vaccine drug product.
J Labelled Comp Radiopharm
; 63(13): 564-571, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32876947
5.
Design and characterization of a self-assembling protein nanoparticle displaying HIV-1 Env V1V2 loop in a native-like trimeric conformation as vaccine antigen.
Nanomedicine
; 16: 206-216, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30576800
6.
A rapid solution-based method for determining the affinity of heroin hapten-induced antibodies to heroin, its metabolites, and other opioids.
Anal Bioanal Chem
; 410(16): 3885-3903, 2018 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-29675707
7.
A simple nonradioactive method for the determination of the binding affinities of antibodies induced by hapten bioconjugates for drugs of abuse.
Anal Bioanal Chem
; 408(4): 1191-204, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26677020
8.
Efficacy, but not antibody titer or affinity, of a heroin hapten conjugate vaccine correlates with increasing hapten densities on tetanus toxoid, but not on CRM197 carriers.
Bioconjug Chem
; 26(6): 1041-53, 2015 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25970207
9.
Synthesis and immunological effects of heroin vaccines.
Org Biomol Chem
; 12(37): 7211-32, 2014 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-24995943
10.
Characterization and optimization of heroin hapten-BSA conjugates: method development for the synthesis of reproducible hapten-based vaccines.
Anal Bioanal Chem
; 406(24): 5927-37, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25084736
11.
A Liquid Chromatography High-Resolution Tandem Mass Spectrometry Method to Quantify QS-21 Adjuvant and Its Degradation Products in Liposomal Drug Formulations.
ACS Omega
; 8(23): 21016-21025, 2023 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37323401
12.
A Rapid Method for Direct Quantification of Antibody Binding-Site Concentration in Serum.
ACS Omega
; 7(30): 26812-26823, 2022 Aug 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35936462
13.
Effect of Preexisting Immunity to Tetanus Toxoid on the Efficacy of Tetanus Toxoid-Conjugated Heroin Vaccine in Mice.
Vaccines (Basel)
; 9(6)2021 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34205869
14.
Synthesis and immunological effects of C14-linked 4,5-epoxymorphinan analogues as novel heroin vaccine haptens.
RSC Chem Biol
; 2(3): 835-842, 2021 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34179783
15.
Immune response to antigen adsorbed to aluminum hydroxide particles: Effects of co-adsorption of ALF or ALFQ adjuvant to the aluminum-antigen complex.
J Control Release
; 275: 12-19, 2018 04 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29432824
16.
A Stable Heroin Analogue That Can Serve as a Vaccine Hapten to Induce Antibodies That Block the Effects of Heroin and Its Metabolites in Rodents and That Cross-React Immunologically with Related Drugs of Abuse.
J Med Chem
; 61(1): 329-343, 2018 01 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29236495
17.
Heroin-HIV-1 (H2) vaccine: induction of dual immunologic effects with a heroin hapten-conjugate and an HIV-1 envelope V2 peptide with liposomal lipid A as an adjuvant.
NPJ Vaccines
; 2: 13, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29263870
18.
Synthesis of Hapten-Protein Conjugate Vaccines with Reproducible Hapten Densities.
Methods Mol Biol
; 1403: 695-710, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27076161
19.
Assessment of RNA carrier function in peptide amphiphiles derived from the HIV fusion peptide.
Peptides
; 79: 27-30, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26988874
20.
Chemical constituents and bioactivities of Glinus oppositifolius.
Pharmacognosy Res
; 7(2): 138-47, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25829787